Immune System Defense Worksheet

Immune System Defence Worksheet

Name:

Date:

Immune system cells defending against pathogens

🛡️ Part 1: Immune System Components

1. Label the diagram below with the correct immune system components:

Word Bank: Skin, White Blood Cells, Antibodies, Mucous Membranes, Lymphocytes

2. Match each immune system component with its correct function:

1. Skin

2. Phagocytes

3. B Cells

4. T Cells

5. Antibodies

A. Produce antibodies to fight specific pathogens

B. Physical barrier preventing pathogen entry

C. Proteins that bind to and neutralise pathogens

D. Coordinate immune response and kill infected cells

E. Engulf and destroy pathogens

🦠 Part 2: How Immune Defence Works

3. Circle the correct order of immune system response when a pathogen enters the body:

Pathogen enters → Antibodies produced → White blood cells respond → Pathogen destroyed

Pathogen enters → White blood cells respond → Antibodies produced → Pathogen destroyed

Antibodies produced → Pathogen enters → White blood cells respond → Pathogen destroyed

4. Fill in the blanks about the three lines of defence:

The first line of defence includes _____________ and _____________ membranes that act as physical barriers.

The second line of defence involves _____________ blood cells like macrophages that engulf pathogens.

The third line of defence uses specific _____________ and _____________ cells to target particular pathogens.

5. Which of the following are functions of white blood cells? (Check all that apply)

Engulf and destroy pathogens

Produce antibodies

Carry oxygen around the body

Remember previous infections

Coordinate immune responses

💉 Part 3: Immunity and Vaccines

6. Explain how memory cells help protect the body from future infections:

7. How do vaccines help prepare the immune system? Circle the best answer:

They kill all pathogens in the body

They introduce weakened pathogens so the immune system can learn to recognise them

They replace the immune system completely

They only work on bacteria, not viruses

8. True or False: Circle T for True or F for False

T / F - Antibodies are specific to particular pathogens

T / F - The immune system only fights bacteria

T / F - Skin is part of the immune system

T / F - All white blood cells have the same function

🎨 Part 4: Design Challenge

9. Create a flow chart showing what happens when a virus enters your body through a cut in your skin. Include at least 5 steps in the immune response:

10. Design a simple poster slogan that explains why good hygiene helps your immune system. Write your slogan and draw a small illustration:

🤔 Part 5: Critical Thinking

11. Explain why someone might get the flu more than once, but usually only gets chickenpox once:

12. A friend says "I never get sick because I have a strong immune system, so I don't need to wash my hands." Explain why this thinking might be problematic:

13. Research Extension: Name one autoimmune disease and briefly explain what happens when the immune system attacks the body's own cells: