Negative Feedback Mechanisms
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Negative Feedback Mechanisms
Case file: the warm bus
On a hot afternoon, Tomasz and Isla are travelling on a crowded city bus. Tomasz has been standing in the sun and his core body temperature begins to rise above its usual value, close to 37°C. Thermoreceptors in the skin and hypothalamus detect the change. The hypothalamus coordinates responses: sweat glands secrete sweat, and skin arterioles widen. Evaporation of sweat and increased blood flow near the skin surface increase heat loss. As temperature moves back towards its normal range, the response becomes less intense. This is negative feedback: the response opposes the original change rather than amplifying it.
- A response that increases a deviation from the normal range
- A response that detects and counteracts a deviation from a set point
- A response that stops receptors detecting any change
- A response that always brings a variable to exactly one value
a) A receptor detects a change in a regulated condition.
b) In negative feedback, the effector response usually amplifies the original deviation.
c) When a variable returns towards its normal range, the corrective response may decrease.
3 printable pages
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